Abstract
To assess the protein and simple sugar content of earwax in pursuit of better ceruminolytic agents. Collected earwax specimens were tested in several media for dissolution before being analyzed for amino acid and carbohydrate content. The samples were obtained from eight random patients requiring ear plug removal. The amino acid composition differs considerably from hair and stratum corneum of glabrous skin. Sugar analysis revealed high levels of galactosamine and galactose. This analysis of proteins and carbohydrates further characterizes earwax. Future ceruminolytic agents must dissolve lipid, keratin, and a monolayer of lipid covalently bound to the epidermal cells, which encourages cellular aggregation.
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