In my blue-light era

Abstract

Grace Lutovsky completed her BSc in chemistry and Spanish from Iowa State University, where she was an undergraduate researcher with Prof. Levi Stanley. During this time, she performed four industrial internships at Iowa Renewable Energy, Pfizer, Zoetis, and Merck. In 2018, she started her doctoral studies under the supervision of Prof. Tehshik Yoon at the University of Wisconsin–Madison, where she is a 3M Science and Technology Fellow. Her research focuses on the development of oxidative photochemical reactions designed to harness widely available nucleophiles in commercial building-block libraries. Grace Lutovsky completed her BSc in chemistry and Spanish from Iowa State University, where she was an undergraduate researcher with Prof. Levi Stanley. During this time, she performed four industrial internships at Iowa Renewable Energy, Pfizer, Zoetis, and Merck. In 2018, she started her doctoral studies under the supervision of Prof. Tehshik Yoon at the University of Wisconsin–Madison, where she is a 3M Science and Technology Fellow. Her research focuses on the development of oxidative photochemical reactions designed to harness widely available nucleophiles in commercial building-block libraries. Iron-mediated modular decarboxylative cross-nucleophile couplingLutovsky et al.ChemMay 4, 2023In BriefWe present a photochemical reaction that enables the direct coupling of carboxylic acids with structurally diverse amines, alcohols, and arenes. This method takes advantage of the ready availability of these building blocks from commercial libraries, the photoactivity of terrestrially abundant iron salts, and the energy of visible light. The result is a versatile oxidative coupling reaction with the potential to streamline rapid synthesis of compound libraries for pharmaceutical discovery. Full-Text PDF