Abstract

The microcirculation constitutes 99% of the circulation in our bodies. It is the most important part of the circulation as it is the exchange surface for nutrients, O2, and CO2, and without it there is no life. In patients with chronic venous disease (CVD), the development of signs and symptoms are also dependent on the state of microcirculation. Multiple studies have used different techniques and histological findings from biopsies to demonstrate microvascular alterations. The work on microvenous reflux in the current paper demonstrates, in a detailed manner, its importance in CVD.

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