Abstract
In this issue of Blood, Kolyada and colleagues elegantly demonstrate the therapeutic utility of a novel, synthetically constructed molecule, the A1 dimer (A1-A1), in preventing anti-β2 glycoprotein I (anti-β2GPI) autoantibody-mediated thrombosis in 2 distinct murine antiphospholipid syndrome (APS) thrombosis models. Current therapies for thrombotic APS entail long-term anticoagulation, with the associated risk of bleeding complications. The findings presented by Kolyada et al raise the possibility of perhaps using this agent to treat thrombotic APS patients in the future, allowing for a reduction in bleeding risk.1
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
