Abstract

BackgroundIt is estimated that over 40 % of the 218,000 people with chronic hepatitis B (CHB) in Australia in 2011 are undiagnosed. A disproportionate number of those with undiagnosed infection were born in the Asia-Pacific region. Undiagnosed CHB can lead to ongoing transmission and late diagnosis limits opportunities to prevent progression to hepatocellular carcinoma (HCC) and cirrhosis.Strategies are needed to increase testing for hepatitis B virus (HBV) (including culturally and linguistically diverse communities, Aboriginal and/or Torres Strait Islander (Indigenous) people and people who inject drugs). General practitioners (GPs) have a vital role in increasing HBV testing and the timely diagnosis CHB. This paper describes the impact of a GP-based screening intervention to improve CHB diagnosis among priority populations in Melbourne, Australia.MethodsA non-randomised, pre-post intervention study was conducted between 2012 and 2013 with three general practices in Melbourne, Australia. Using clinic electronic health records three priority populations known to be at increased CHB risk in Australia (1: Asian-born patients or patients of Asian ethnicity living in Australia; 2: Indigenous people; or 3): people with a history of injecting drugs were identified and their HBV status recorded. A random sample were then invited to attend their GP for HBV testing and/or vaccination. Baseline and follow-up electronic data collection identified patients that subsequently had a consultation and HBV screening test and/or vaccination.ResultsFrom a total of 33,297 active patients, 2674 (8 %) were identified as a priority population at baseline; 2275 (85.1 %) of these patients had unknown HBV status from which 338 (14.0 %) were randomly sampled. One-fifth (n = 73, 21.6 %) of sampled patients subsequently had a GP consultation during the study period; only four people (5.5 %) were subsequently tested for HBV (CHB detected in n = 1) and none were vaccinated against HBV.ConclusionCHB infection is an important long-term health issue in Australia and strategies to increase appropriate and timely testing are required. The study was effective at identifying whether Asian-born patients and patients of Asian had been tested or vaccinated for HBV; however the intervention was not effective at increasing HBV testing.

Highlights

  • It is estimated that over 40 % of the 218,000 people with chronic hepatitis B (CHB) in Australia in 2011 are undiagnosed

  • This paper presents results of a pilot study conducted with general practice clinics to identify people at increased risk of hepatitis B virus (HBV) in three priority populations (Asian-born patients or patients of Asian ethnicity, Indigenous people or people who inject drugs (PWID)), and increase HBV testing and, where appropriate, HBV vaccination in these populations

  • A total of 2674 (8 %) of these patients were identified as a priority population for HBV testing and comprised the source population for the intervention

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Summary

Introduction

It is estimated that over 40 % of the 218,000 people with chronic hepatitis B (CHB) in Australia in 2011 are undiagnosed. Undiagnosed CHB can lead to ongoing transmission and late diagnosis limits opportunities to prevent progression to hepatocellular carcinoma (HCC) and cirrhosis. Despite being a leading cause of HCC globally, the asymptomatic nature of chronic hepatitis B (CHB) infection has resulted in a large number of undiagnosed cases [1,2,3]. Current estimates suggest there are 218,000 people living with CHB in Australia; over half (56 %) born overseas and one-third (38 %) of this group were born in the Asia/Pacific region, a region with several countries with high and intermediate CHB prevalence [3, 6]. Undiagnosed CHB can lead to ongoing transmission, while late diagnosis limits opportunities to prevent progression to HCC or cirrhosis [4]. It is imperative that those living with CHB are diagnosed in an timely manner as treatment significantly reduces the risk of HCC [13], and early detection of HCC is associated with improved 5-year survival rates [14]

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