Abstract
Introduction and Aim:Atherosclerotic cardiovascular disease (ASCVD)and Framingham score (FRS) are two important scores used for the prediction of coronary events in an individual.Both of these scores do not account for certain known predisposing factors such as BMI, duration of diabetes, LDL cholesterol and glycemic index levels among type 2 diabetes mellitus (T2DM) subjects. So, this study aims to assess whether addition of any of these important risk factors might help in improving these scoring systems in T2DM patients.
 Methodology: Our study is a cross-sectional study which included 320 T2DM patients without CAD and 120 T2DM patients with CAD. Duration of T2DM, BMI, glycated hemoglobin and fasting lipid profile values of the T2DM patients were recorded from the Laboratory information system.
 Results: IBM Statistical Package for the Social Sciences (SPSS) 16 version was used for statistical analysis. T2DM patients with CAD had more years of duration of T2DM than the patients without CAD and a significant association was found (p=.045*). A strong significant positive correlation was observed between FRS score and duration of T2DM in diabetic patients with CAD (r=.331, p=<.0001*).
 Conclusion:Our observations imply that inclusion of important parameter such as duration of T2DM might improve in better calculation of these risk scores in T2DM patients. Future studies are needed to assess the performance of existing risk scores by including important parameter such as duration of diabetes which might help in improving these scoring systems in T2DM patients.
Highlights
Introduction and AimAtherosclerotic cardiovascular disease (ASCVD) and Framingham score (FRS) are two important scores used for the prediction of coronary events in an individual
Our observations imply that inclusion of important parameter such as duration of type 2 diabetes mellitus (T2DM) might improve in better calculation of these risk scores in T2DM patients
Future studies are needed to assess the performance of existing risk scores by including important parameter such as duration of diabetes which might help in improving these scoring systems in T2DM patients
Summary
Atherosclerotic cardiovascular disease (ASCVD) and Framingham score (FRS) are two important scores used for the prediction of coronary events in an individual. Both of these scores do not account for certain known predisposing factors such as BMI, duration of diabetes, LDL cholesterol and glycemic index levels among type 2 diabetes mellitus (T2DM) subjects. An Indian study showed the FRS-CVD risk assessment tool to be the best among all the available cardiovascular risk assessment tools with prediction rate of 51.9% whereas WHO risk charts and ASCVD risk tool were found to be the worst with prediction rates ranging from 16.2% to 28.3% [4].
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