Abstract
Systemic lupus erythematosus in children is a multisystem disease with extensive organ involvement characterized by its chronic, fluctuating and unpredictable course. The physical, emotional and social effects of systemic lupus erythematosus significantly impact the health-related quality of life (HRQOL) of patients. In the last several years, the need for addressing HRQOL in children with systemic lupus erythematosus has been recognized and there has been significant progress. The current tools offer significantly greater advantages compared with the older scales used to measure HRQOL in these children. The relationship between HRQOL and disease activity and damage has been examined. Research is underway to examine HRQOL globally across different countries and cultures.
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