Abstract
Newborns with harlequin ichthyosis and collodion babies (CB) have similar physiologic deficits and needs requiring intensive neonatal care. 1 Prado R. Ellis L.Z. Gamble R. Funk T. Arbuckle H.A. Bruckner A.L. Collodion baby: an update with a focus on practical management. J Am Acad Dermatol. 2012; 67: 1362-1374 Abstract Full Text Full Text PDF PubMed Scopus (46) Google Scholar Yet the perception lingers that the prognosis for harlequin ichthyosis is poor whereas that for CB is good. Examination of intrinsic and extrinsic factors influencing prognosis lead us to conclude that the outlook for babies with harlequin ichthyosis can be improved. High survival rate of harlequin ichthyosis in JapanJournal of the American Academy of DermatologyVol. 70Issue 2PreviewTo the Editor: Harlequin ichthyosis (HI) (OMIM 242500) is one of the most severe genetic skin disorders, and its clinical features at birth include severe ectropion, eclabium, flattening of the ears, and large, thick platelike scales over the entire body. Neonatal death is common. Full-Text PDF
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