Improving of reparative osteogenesis in patients diagnosed with chronic generalised periodontitis

Abstract

Pathological condition of periodontal structures presents a most complicated and wide spread problem in modern stomatology. According to data provided by WHO the periodontal disorders affect from 55 % up to 99% of population between the ages of 15 to 20 years and varies from 65% up to 98% in the age group from 35 to 44 years. It has to be emphasized that there is none a single efficient treatment of generalized chronic periodontitis. Therefore, it is vital to improve the existent methods and find the new ones in diagnosis and management of periodontal disorders. The latter remains an actual subject of modern periodontology and surgical stomatology and exceeds a strategic doctrine on the whole. The article demonstrates the results gained by surgical treatment of chronic generalized periodontitis, III degree of severity obtained by administration of bone-plastic material “Osteoplast-К” together with barrier membrane “Parodoncol” and pharmacological agent with immunomodulating effect «Extra Erbisol». We have observed the high efficiency of the recommended treatment that was proved by positive dynamic of alkali nephosphatase (ALP) in the blood serum of the main group over the period from 4 to 30 days by 21,7% comparing to the initial level (р < 0,05). This investigation suggests that there is higher alveolar bone regeneration in the patients from the main group after the introduced treatment comparing to the control group. On the other hand, activity of aminotranspherase did not changed significantly before and after operation in the control group. The findings also prove that there is no harmful influence of pharmacological agents used in this scheme.