Abstract

Nursing home (NH) resident populations are exposed to complex clinical conditions, leading to high risk for iatrogenic events, functional decline, and death. This requires an expert management.1 NH residents differ from other patients in many aspects. First, aging causes a change in drug metabolism (pharmacokinetics) and target organ sensitivity (pharmacodynamics). Second, NH residents receive more medications than noninstitutionalized older people: on average, 7 to 8 medications, including use of inappropriate therapies.

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