Abstract

Close collaboration between specialists from diverse backgrounds and working in different scientific domains is an effective strategy to overcome challenges in areas that interface between biology, chemistry, physics and engineering. Communication in such collaborations can itself be challenging. Even when projects are successfully concluded, resulting publications - necessarily multi-authored - have the potential to be disjointed. Few, both in the field and outside, may be able to fully understand the work as a whole. This needs to be addressed to facilitate efficient working, peer review, accessibility and impact to larger audiences. We are an interdisciplinary team working in a nascent scientific area, the repurposing of DNA as a storage medium for digital information. In this note, we highlight some of the difficulties that arise from such collaborations and outline our efforts to improve communication through a glossary and a controlled vocabulary and accessibility via short plain-language summaries. We hope to stimulate early discussion within this emerging field of how our community might improve the description and presentation of our work to facilitate clear communication within and between research groups and increase accessibility to those not familiar with our respective fields - be it molecular biology, computer science, information theory or others that might become relevant in future. To enable an open and inclusive discussion we have created a glossary and controlled vocabulary as a cloud-based shared document and we invite other scientists to critique our suggestions and contribute their own ideas.

Highlights

  • As we tackle increasingly complex issues throughout science, a breadth of knowledge is often necessary to devise novel solutions — something frequently achieved through interdisciplinary collaborations

  • We work within an emerging field in synthetic biology, repurposing DNA as a storage medium for digital information

  • We propose to refer to DNA sequences that store digital information as inDNA

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Summary

10 Jan 2018 report report

1. Robert Grass , ETH Zurich (Swiss Federal Institute of Technology in Zurich), Zürich, Switzerland. Any reports and responses or comments on the article can be found at the end of the article. Keywords DNA-storage, digital information storage in DNA, synthetic biology, glossary, communication, controlled vocabulary, short plain-language summaries, interdisciplinary collaboration. This article is included in the EMBL-EBI collection

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10. Schumacher B
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