Abstract
Infusion techniques are an important advance in intravenous cholangiography, and I was therefore most interested to read the article by Drs. Nolan and Gibson in your September issue. I fear, however, that this paper may encourage the unnecessary and possibly harmful escalation of Biligrafin dosage. Some patients apparently received 90 ml. of Biligrafin Forte. This dose contains 45 g of the methylglucamine salt of Biligrafin with a total iodine content of 22·5 g. For comparison one might consider the oral preparation of Telepaque. A double dose (6 g) of this substance, which might be required for a very large patient, contains only 4g of iodine.
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