Abstract
Thermal stability of proteins can be improved by evolutionary molecular engineering, without the knowledge about 3D structures of the proteins nor the principle that governs the protein stability. The method will provide a way of improving the thermal stability of industrially important proteins. It can also be used as a tool to study protein stability. There are a substantial number of examples now. Our recent study suggested that it is easy to obtain thermo-stabilized proteins by single-base substitution. Although, it requires further improvement of the method to obtain mutants with double-base substitution within a codon.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
