Abstract
Introduction Elastin-like polypeptide (ELP) supplementation was previously reported to enhance the physical properties of mineral trioxide aggregate (MTA). The aim of this study was to investigate the effect of ELP supplementation on the bonding properties of MTA to dentin. Methods Two types of ELPs were synthesized and mixed with MTA in a 0.3 liquid/powder ratio. The push-out bond strength test and interfacial observation with scanning electron microscopy were performed for ELP-supplemented MTA. The porosity of MTA fillings in the cavity was observed with microcomputed tomography. The stickiness, flow rate, and contact angle were additionally measured for potential increased bonding properties. Results ELP supplementation improved the bond strength of MTA to dentin. MTA supplemented by a specific ELP exhibited a less porous structure, higher stickiness, and higher flow rate. ELPs also decreased the contact angle to dentin. Conclusions This research data verifies that ELP improves the bonding properties of MTA to a tooth structure. The sticky and highly flowable characteristics of ELP-supplemented MTA may provide intimate contact with dentin and supply a less porous cement structure, which might improve the bonding properties of MTA.
Highlights
Elastin-like polypeptide (ELP) supplementation was previously reported to enhance the physical properties of mineral trioxide aggregate (MTA)
We evaluated the bond strength of MTA to dentin and performed supportive experiments to explain the reasons for the improved bonding properties in ELP-supplemented MTA
All groups commonly exhibited attached MTA pieces on the surface, open dentinal tubules were often observed in the deionized water (DW) group and rarely in the V125 and V125E8 groups
Summary
Elastin-like polypeptide (ELP) supplementation was previously reported to enhance the physical properties of mineral trioxide aggregate (MTA). The sticky and highly flowable characteristics of ELP-supplemented MTA may provide intimate contact with dentin and supply a less porous cement structure, which might improve the bonding properties of MTA. One typical example of discontinuity is a pulp exposure, which is the abrupt appearance of soft tissue inside the tooth due to the breakdown of dentin continuity through mechanical or pathological reasons. Overextensions to periodontal tissue and washouts of MTA may occur on large defects due to the slow setting time and low mechanical properties of MTA at the initial stage [8, 9] To overcome these limitations, some studies reported the use of an internal matrix, such as a calcium sulfate barrier and resorbable collagen for the repair of large defects [3, 10]. A successful treatment of large discontinuities of the tooth structure remains a challenge
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