Improvement of laboratory diagnostics of metabolic syndrome with arterial hypertension in elderly patients.

Abstract

Metabolic syndrome (MS) is considered an age-associated pathology, often combined with hypertension (AH) and has a high prevalence in the elderly. However, a comparative study of the broad spectrum of proinflammatory and anti-inflammatory interleukins with an assessment of their informative value in elderly patients WITH MS with AH was not carried out. The aim of the study was to improve the diagnosis of MS with hypertension in elderly patients based on the analysis of the informativity of serum interleukins.. The content of interleukins in serum was studied in 86 patients with MS and AH aged 60-75 years and 35 persons without MS and AH, comparable in age and sex. It was found that for the diagnosis of S in combination with AH as the leading laboratory markers of systemic immunity it is necessary to use highly informative IL-8, IL-1B, IL-4 and IL-10. Other serum interleukins (Il-6, IL-2, TNF-α, interferon-ɣ, interferon-α and IL-18) can be considered as additional markers in the diagnosis of MS with hypertension in the elderly.