Abstract

Nowadays the efficient use of an obturator probe has remained not high enough, and is also accompanied with a number of particular complications. A study was performed to increase the effectiveness of primary hemostasis using the Sengstaken − Blackmore probe with a coating having hemostatic, antibacterial and regenerative properties in an acute episode of bleeding from varicose veins of the esophagus and stomach in the patients with liver cirrhosis and portal hypertension. A prospective, controlled, randomized study of the treatment results for the patients with an acute episode of bleeding from varicose veins of the esophagus and stomach on the background of liver cirrhosis complicated by portal hypertension was carried out. In the main group of patients, an ointment of a combined composition (antibacterial component, proline, oxidized cellulose) was preliminarily applied to the balloons of the obturator probe, which contributed to quite an effective hemostasis. In the patients using the standard methodology, the changes identified in laboratory and instrumental studies indicated unstable hemostasis. Thus, the use of an ointment of a combined composition to treat the balloons of the obturator probe prevents the damaging effect on a mucous membrane of the esophagus and accelerates its regeneration, prevents the aggravation of liver functional state by reducing the frequency of relapses and can be used as an independent method for treating the patients with bleeding from varicose veins of esophagus on the background of portal hypertension, and after performing an endoscopic sclerotherapy. Key words: portal hypertension, liver cirrhosis, bleeding, esophageal and gastric varices, proline, obturator probe.

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