Improvement of Atrophic Acne Scar and Skin Complexity by Combination of Aqueous Human Placenta Extract and Mesenchymal Stem Cell Mesotherapy

Ruchee Phonchai,Supaluk Brameld,Parinya Noisa,Supansa Nilubol,Pimjai Naigowit,Bunchob Ubonsaen

doi:10.4236/jcdsa.2020.101001

Ruchee Phonchai, Supaluk Brameld + Show 4 more

Open Access

https://doi.org/10.4236/jcdsa.2020.101001

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Abstract

Atrophic scars, a permanent complication of severe acne, have negative effect on psychology in adolescent. The treatment of atrophic scar is depended on types of scar and it is difficult to improve by a single treatment. Mesenchymal stem cell is a scientific approval for surgery scar treatment and wound healing. We present a case report of female presented with atrophic acne scar distributed on both cheeks. The case aims to prove that the combination of MSCs and aqueous human placenta extract (RGF&#174) contained bioactive therapeutic molecules obviously promoted the improvement of skin scar to reach the optimal outcomes. We first found that MSCs-contained human placenta extract solution combination subcision improves the atrophic acne scar and skin complexity by enhancement of skin cell regeneration.

Highlights

Atrophic acne scar is often a permanent complication of acne vulgaris
The case aims to prove that the combination of Mesenchymal stem cells (MSCs) and aqueous human placenta extract (RGF ) contained bioactive therapeutic molecules obviously promoted the improvement of skin scar to reach the optimal outcomes
We first found that MSCs-contained human placenta extract solution combination subcision improves the atrophic acne scar and skin complexity by enhancement of skin cell regeneration

Summary

Introduction

Atrophic acne scar is often a permanent complication of acne vulgaris. It has a high prevalence in puberty and impacts on physical appearance and mental health [1]. MSCs and human placenta extracts mesotherapy are the best treatment for skin cell regeneration and repairing tissue [16] [17] [18]. The stem cell may be useful for the best therapeutic strategies, whether it be single or combined therapy, in the treatment of atrophic acne scars while reducing or avoiding the side effects and complications. This case report presents a female with atrophic scar in both cheeks. The case aims to prove the combination of MSCs and aqueous human placenta extract contained bioactive therapeutic molecules obviously promoted the improvement of skin scar to reach the optimal outcomes

Case Report

Discussion

Findings

Conclusion