Abstract

Hypertrophic pulmonary osteoarthropathy is a syndrome characterized by clubbing of the fingers and toes, arthritis, periostitis, soft tissue swelling, and autonomic dysfunction. It is usually associated with intrathoracic neoplasm [1 , 2]. Hypertrophic pulmonary osteoarthropathy has been found in 4%-i 2% of patients with bronchogenic carcinoma [3]. Bone scanning with 99mTc phosphate compounds has been shown to be a sensitive method for detecting hypertrophic pulmonary osteoarthropathy [4-6]. Reversal of bone scan abnormality after removal of the primary tumor has been demonstrated [4, 5]. We describe a patient with squamous cell carcinoma of the lung with metastasis to the radius, in whom improvement in hypertrophic pulmonary osteoarthropathy occurred after radiation treatment of the metastasis. The primary lung tumor was not treated. This improvement was clearly shown on repeat bone scan. To our knowledge, this is the first report of such a case.

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