Abstract

SELECTION OF NATURAL ANTI-A AND ANTI-B TEST SERUMS OF UNUSUALLY HIGH ISOAGGLUTININ TITER AND IMPORTANCE OF THEIR USE IN GROUPING OF BLOODS PRIOR TO TRANSFUSION With the discovery of the human blood groups by Landsteiner1at the turn of this century, the vast majority of dangerous reactions were eliminated, and the transfusion of blood became a relatively safe procedure. Landsteiner observed that the cells of some bloods when placed with the serums of others would clump together. This phenomenon was called agglutination.2The serum factor in this phenomenon was called the agglutinin, and the cell factor was called the agglutinogen. On the basis of the presence or absence of such serum and cell factors all human bloods can be classified into four groups. Landsteiner was able to divide human blood into three groups.3The fourth and rarest group was added by von Decastello4and Sturli in

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