Abstract
Introduction: Real-time endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a recently introduced method of biopsy of the mediastinal lymph nodes. This is a safe and minimally invasive and save procedure. The material can be obtained as a smear or cell block (CB). Aims: This study focused on the role of cell block (CB) analysis in determining the diagnostic yield of EBUS-TBNA. Objective of the study was to assess the effectiveness of the new method of collecting CB. Methods: We included 25 patients (different causes). We performed 32 biopsies nodes (twice each). For the biopsy a cytological 22 G needle was used. First biopsy: CB was taken by conventional method - needle was purged by air. Second biopsy: CB was taken by new method – needle was rinsed by cytospin (RCB). Diagnostic yield on cell block versus rinsed cell block was recorded. Cell blocks were reviewed by an experienced pathologist to determine diagnostic accuracy. Results: Diagnostic material was found in CB n=11 (34%) vs.RCB n= 16 (50%). No statistical significance was found (p=0,2). Do not observed any side effects. Conclusions: The data demonstrate no remarkable difference in diagnostic yield. We observed a nonsignificant 16% advantage in favor of the rinsed CB. It requires further research on a larger group of patients. Do not observed any side effects.
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