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Abstract
In high-field NMR microscopy rapid single-shot imaging methods, for example, echo planar imaging, cannot be used for determination of the apparent diffusion tensor (ADT) due to large magnetic susceptibility effects. We propose a pulse sequence in which a diffusion-weighted spin-echo is followed by multiple gradient-echoes with additional diffusion weighting. These additional echoes can be used to calculate the ADT and T 2 ∗ maps. We show here that this results in modest but consistent improvements in the accuracy of ADT determination within a given total data acquisition time. The method is tested on excised, chemically fixed rat spinal cords.
Published Version
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