Abstract
Drug delivery systems offer the potential to improve the therapeutic index of chemotherapeutic agents via targeting the antitumor drug to its desired site of action, and hence, increasing the drug concentration in cancer cells and decreasing its concentration in healthy cells. Several nano-sized drug carriers, such as nanoparticles, liposomes, micells and polymer-drug conjugates, have been investigated in order to minimize side effects of anticancer drugs and enhance the antitumoral drug efficacy in cancer therapy.
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