Abstract

The E. Coli K12 UDP-Gal mutase inhibitor 1 was prepared from d-glucose in 5 steps (42% overall yield). The 4-azido galactose derivative 11 , leading to 1 , was formed by treatment of galactose dithioacetal 7 with mercuric oxide and mercuric chloride in acetone. To obtain 7 , acetal 3 was tosylated or triflated and treated with NaN 3.

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