Improved Nickel-Catalyzed Cross-Coupling Reaction Conditions between ortho-Substituted Aryl Iodides/Nonaflates and Alkylzinc Iodides in Solution and in the Solid-Phase

Abstract

ortho-Substituted aryl iodides and nonaflates undergo nickel-catalyzed cross-coupling reactions with functionalized alkylzinc iodides in the solid-phase as well as in solution providing high HPLC purities and good yields.