Abstract
Background CE-MRA following the injection of a gadolinium-based contrast agent (GBCA) bolus is widely used in clinical assessment of vascular dynamics and tissue perfusion (1,2). Although keyhole techniques with an increased number of central k-space updates further improved contrast kinetics information, spatial resolution remains limited. Alternatively applied view sharing approaches also result in prolonged temporal footprints with possible temporal blurring or reconstruction artifacts. Sparse, incoherent sampling approaches and iterative reconstruction techniques have proven successful particularly in dynamic MR imaging (3). We sought to evaluate the impact of iterative reconstruction techniques on dynamic contrast enhanced MRA of the thoracic aorta.
Highlights
CE-MRA following the injection of a gadolinium-based contrast agent (GBCA) bolus is widely used in clinical assessment of vascular dynamics and tissue perfusion (1,2)
TWIST was followed by accelerated static MRA (GRAPPA R = 3) with 0.9 × 0.9. × 1.2 mm[3] resolution in 22 s acquisition
In comparison to static high-res MRA, iterative reconstruction resulted in non-statistically significant differences for overall aortic CNR while standard reconstruction was significantly inferior
Summary
CE-MRA following the injection of a gadolinium-based contrast agent (GBCA) bolus is widely used in clinical assessment of vascular dynamics and tissue perfusion (1,2). Keyhole techniques with an increased number of central k-space updates further improved contrast kinetics information, spatial resolution remains limited. Applied view sharing approaches result in prolonged temporal footprints with possible temporal blurring or reconstruction artifacts. Incoherent sampling approaches and iterative reconstruction techniques have proven successful in dynamic MR imaging (3). We sought to evaluate the impact of iterative reconstruction techniques on dynamic contrast enhanced MRA of the thoracic aorta
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