Abstract

Acute lymphoblastic leukemia is a well-known type of pediatric cancer that affects the blood and bone marrow. If left untreated, it ends in fatal conditions due to its proliferation into the circulation system and other indispensable organs. All over the world, leukemia primarily attacks youngsters and grown-ups. The early diagnosis of leukemia is essential for the recovery of patients, particularly in the case of children. Computational tools for medical image analysis, therefore, have significant use and become the focus of research in medical image processing. The particle swarm optimization algorithm (PSO) is employed to segment the nucleus in the leukemia image. The texture, shape, and color features are extracted from the nucleus. In this article, an improved dominance soft set-based decision rules with pruning (IDSSDRP) algorithm is proposed to predict the blast and non-blast cells of leukemia. This approach proceeds with three distinct phases: (i) improved dominance soft set-based attribute reduction using AND operation in multi-soft set theory, (ii) generation of decision rules using dominance soft set, and (iii) rule pruning. The efficiency of the proposed system is compared with other benchmark classification algorithms. The research outcomes demonstrate that the derived rules efficiently classify cancer and non-cancer cells. Classification metrics are applied along with receiver operating characteristic (ROC) curve analysis to evaluate the efficiency of the proposed framework.

Highlights

  • During the last few decades, digital image analysis has been enriched with significant advancements and new techniques

  • We describe an image process by which a leukemia nucleus is segmented in the image applying the particle swarm optimization algorithm (PSO)

  • It is deduced that the overall classification accuracy of the proposed IDSSDRP is 98.08%, 97.12%, 99.04%, 97.60%, and 95.67% for GLCM_0, GLCM_45, GLCM_90, GLCM_135, and shape and colour datasets respectively

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Summary

Introduction

During the last few decades, digital image analysis has been enriched with significant advancements and new techniques. In the field of medical image analysis, various kinds of image processing and analysis techniques have been developed and applied to extract clinical data from the captured images. Despite these advancements in science and technology, in oncology studies, medical practitioners experience uncertainties when classifying malignant features. This constraint has prompted many researchers to design frameworks to analyze the image and to diagnose the disease accurately so that better treatment could be given to the patient at the right time. Leukemia is a collective term applied to a group of malignant diseases with significant

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