Abstract
To develop new and improved compounds for future use against drug-resistant bacteria or for chemical modification, it is necessary to continue to screen for new metabolites and evaluate the potential of less known and new bacterial taxa. Selective isolation of rare actinomycetes is one of the major targets of industrial microbiologists in the search for novel compounds with therapeutic activity. Amycolata and Amycolatopsis have also been target for industrial microbiologists in this search. An improved technique, involving the microwave irradiation of soil samples followed by exposure to polyvalent Nocardia/Rhodococcus phages in order to selectively detect the members of the genera Amycolata and Amycolatopsis, has been developed. This improved technique reduced the numbers of colony forming units of unwanted bacteria on isolation plates and hence increased the chances of detecting novel Amycolata and Amycolatopsis species.
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