Abstract

An improved and quick cleanup method has been developed for the liquid chromatographic determination of 21 N-methylcarbamate pesticides and 10 of their metabolites in grains, fruits and vegetables. Various types of solid phase extraction columns have been tested for the cleanup step in order to replace the time-consuming cleanup method found in the literature. Aminopropyl-bonded silica columns proved to be superior to unbonded silica or octyl, octadecyl, cyanopropyl and diol-bonded silica. For all 16 types of matrices tested, a single column cleanup step appeared to be satisfactory.

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