Abstract

Background: Considering that inflammation is involved in many degenerative conditions, some derivatives of tolfenamic acid, naproxen and indomethacin were synthesised and evaluated biologically. They were found to possess increased anti-inflammatory activity, being more potent than the parent drugs. Keywords: Anti-inflammatory activity, brain ischemia-reperfusion, liver injury, indomethacin, naproxen, tolfenamic acid.

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