Abstract
BackgroundTo evaluate the effects of pretreatment for dry eye disease (DED) on the accuracy of intraocular lens (IOL) power calculation.MethodsPatients who underwent uneventful cataract surgery were included in the study. IOL power was determined using the SRK/T and Barrett Universal II (Barrett) formulas. The patients were divided into non-pretreatment and pretreatment groups, and those in the pretreatment group were treated with topical 0.5% loteprednol etabonate and 0.05% cyclosporin A for 2 weeks prior to cataract surgery. Ocular biometry was performed in all groups within 2 days before surgery. The mean prediction error, mean absolute error (MAE), and proportions of refractive surprise were compared between the non-pretreatment and pretreatment groups at 1 month postoperatively. Refractive surprise was defined as MAE ≥ 0.75D.ResultsIn a total of 105 patients, 52 (52 eyes) were in the non-pretreatment group and 53 (53 eyes) in the pretreatment group. The MAE was 0.42 ± 0.33, 0.38 ± 0.34 (SRK/T, Barrett) and 0.23 ± 0.19, 0.24 ± 0.19 in the non-pretreatment and pretreatment groups, respectively (p < 0.001/=0.008). The number of refractive surprises was also significantly lower in the pretreatment group. [non-pretreatment/pretreatment: 9/2 (SRK/T); 8/1 (Barrett); p = 0.024/0.016]. Pretreatment of DED was related to a reduction in postoperative refractive surprise. [SRK/T/Barrett: OR = 0.18/0.17 (95% CI: 0.05–0.71/0.05–0.60), p = 0.014/0.006].ConclusionsThe accuracy of IOL power prediction can be increased by actively treating DED prior to cataract surgery.
Highlights
The number of cataract surgeries has grown significantly in recent years due to an increase in lifespan in the elderly population [1]
We investigated whether shortterm pretreatment of dry eye disease (DED) using topical loteprednol etabonate (LE) and cyclosporin A (CsA) before cataract surgery improves the accuracy of intraocular lens (IOL) power calculation
There were no differences in the axial length (AL), average K value, anterior chamber depth, tear film breakup time, ocular surface staining score, and tear secretion with the Schirmer test between the non-pretreatment and pretreatment groups
Summary
The number of cataract surgeries has grown significantly in recent years due to an increase in lifespan in the elderly population [1]. According to the preoperative treatment algorithm for ocular surface disorders from the recent clinical committee of the American Society of Cataract and Refractive Surgery, treatment of DED prior to cataract surgery can optimize surgical outcomes and patient satisfaction [10]. It is important because DED can increase the variability in preoperative anterior corneal power measure, leading to inaccurate IOL power prediction [11, 12]. To evaluate the effects of pretreatment for dry eye disease (DED) on the accuracy of intraocular lens (IOL) power calculation
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