Abstract
Imported Chikungunya Virus Strains, Taiwan, 2006–2009
Highlights
A phylogenetic tree based on 49 chikungunya virus (CHIKV) partial envelope 1 (E1) gene sequences was constructed to trace the origins of the 14 CHIKV strains reported in this study (Figure)
The imported Singapore/ 0611aTw/2006 and India/0812cTw/ 2008 strains belong to the Central/East/ South African genotype and are clustered with several India/2006 (IND06-AP3, IND-06-TN1 and DRDE06), India/Kokkarayapalli/2008, and Singapore/EHIss622/2008 strains, which have an alanine at the position E1–226
Phylogenetic analysis demonstrated that CHIKV strains isolated from Indonesia during 2007–2008 remain stable and belong to the Asian genotype, whereas the other 7 isolates from Singapore, Bangladesh, Malaysia, and India belong to the Central/East/South African genotype
Summary
Previous phylogenetic studies showed that chikungunya virus (CHIKV) strains were clustered into 3 distinct genotypes separated primarily by location into West African, Central/East/South African, and Asian genotypes [1,2]. Earlier outbreaks in Thailand, Cambodia, Vietnam, Myanmar, the Philippines, Malaysia, Indonesia, Pakistan, and India during 1960–1999 were caused by strains of the Asian genotype [2]. Recent studies have shown that different lineages of CHIKV strains of the Central/East/South African genotype have expanded locally and spread to new areas in Africa, Europe, and Asia and caused epidemics [2,3,4,5,6,7].
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