Abstract
Research related to the health of humans should have the potential to advance scientific understanding or improve the treatment or prevention of disease. Reports of clinical research are important to many groups, especially other researchers, clinicians, systematic reviewers, and patients. Nonpublication of the findings of some research studies, either through suppression of complete studies or selective reporting within publications, always diminishes the evidence base. Inadequate reporting of methodology can also seriously impede assessment of the reliability of published articles. Reporting guidelines provide structured advice on the minimum information to be included in an article reporting a particular type of health research. Journals have a key role in helping to improve the literature by requiring the full and transparent reporting of research. Web-enabled reporting guidelines are one possibility as are machine'readable language software to help populate checklists automatically.
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