Abstract
Objectives: A simple and appropriate risk index is still required to show the patient's nutritional status undergoing coronary artery bypass graft (CABG) surgery. This study aimed to evaluate the Prognostic Nutritional Index (PNI) value as a predictor of in-hospital mortality in patients undergoing CABG surgery. Methods: In this study, we scanned the medical data of 742 patients’ who underwent on-pump CABG surgery retrospectively. Patients' were divided into two groups based on the PNI cut-off value (high-risk group, PNI < 45.85, n = 230; low-risk group, PNI ≥ 45.85, n = 512). Results: To analyze the factors affecting in-hospital mortality in the postoperative period, univariate and multivariate logistic regression analysis was performed. In univariate analysis, advanced age (Odds ratio (OR): 1.219, 95% confidence interval (CI): 1.194-2.669, p < 0.001), left ventricular ejection fraction (LVEF) (OR: 3.471, 95% CI: 2.854-6.927, p < 0.001), total perfusion time (OR: 0.876, 95% CI: 0.690-0.954, p = 0.012), intra-aortic balloon pump (IABP) use (OR: 2.148, 95% CI: 1.394-2.889, p = 0.002), preoperative high creatinine (OR: 1.229, 95% CI: 1.066-2.118, p = 0.019), low lymphocyte count (OR: 0.879, 95% CI: 0.789-0.945, p = 0.017), low albumin (OR: 1.682, 95% CI: 1.433-2.765, p = 0.003), high C-reactive protein (CRP) (OR: 1.0.790, 95% CI: 0.678-0.927, p = 0.042) and low PNI (OR: 1.290, 95% CI: 1.119-1.654, p < 0.001) were correlated with the postoperative mortality. In multivariate logistic regression analysis, advanced age (OR: 1.145, 95% CI: 1.110-1.938, p = 0.017), LVEF (OR: 2.916, 95% CI: 1.768-4.928, p < 0.001), IABP use (OR: 1.880, 95% CI: 1.350-2.554, p = 0.032) and PNI (OR: 0.932, 95% CI: 0.889-0.978, p = 0.004) were independent predictors of mortality. Conclusions: In on-pump CABG surgery, postoperative mortality is associated with low preoperative PNI, and can be a useful and suitable parameter for preoperative risk evaluation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
