Abstract

The study by Whelton et al1 shows that resting heart rate is independently associated with arterial stiffness. Arterial stiffness was quantified as distensibility and determined from ultrasound measurements of carotid diameter and MRI measurements of aortic diameter. Distensibility, computed from the relative change in carotid diameter and relative change in aortic area for a cardiac cycle divided by the brachial pulse pressure, was related to heart rate that spanned an average range of 50.9 to 78.1 bpm between the first and the last quintile, respectively (Table 1 …

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