Abstract
Two experiments using the technique of intragastric infusion of isotonic saline were conducted to examine the role of postingestional factors in the regulation of sodium intake by sodium deficient rats. Experiment 1 demonstrated that the sodium appetite of a Formalin injected rat is satiated by intragastric infusion of sufficient NaCl to restore the rat's sodium balance. Experiment 2 demonstrated that a sodium deficient rat's bar pressing for NaCl is influenced by the amount of NaCl previously intragastrically infused. As the amount of saline delivered intragastrically to the rats increased, the amount of saline they worked for decreased. In addition, the infused sodium apparently was as effective as sodium taken orally in satiating the rats' sodium appetites.
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