Abstract
Detection and characterization of focal liver lesions. Due to its excellent soft tissue contrast, the availability of liver-specific contrast agents and the possibility of functional imaging, magnetic resonance imaging (MRI) is the method of choice for the evaluation of focal liver lesions. Diffusion-weighted imaging (DWI) enables generation of functional information about the microstructure of atissue besides morphological information. In the detection of focal liver lesions DWI shows abetter detection rate compared to T2w sequences and aslightly poorer detection rate compared to dynamic T1w sequences. In principle, using DWI it is possible to distinguish malignant from benign liver lesions and also to detect atherapy response at an early stage. For both detection and characterization of focal liver lesions, DWI represents apromising alternative to the morphological sequences; however, amore detailed characterization with the use of further sequences should be carried out particularly for the characterization of solid benign lesions. For the assessment and prognosis of therapy response, DWI offers advantages compared to morphological sequences. For the detection of focal liver lesions DWI is in principle sufficient. After visual detection of asolid liver lesion amore detailed characterization should be carried out using further sequences (in particular dynamic T1w sequences). The DWI procedure should be used for the assessment and prognosis of atherapy response.
Published Version
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