Importance of active and passive smoking as one of the risk factors for female sexual dysfunction in Chinese women

Abstract

Objective To assess possible risk factors for female sexual dysfunction (FSD), aiming especially at smoking in China. Methods Female Sexual Function Index (FSFI) for assessing FSD; 621 women (24–75 years) divided into ‘group FSD’ (FSFI≤ 26.55) and ‘group No FSD’ (FSFI > 26.55). Univariate and multivariate analysis to detect potential risk factors for FSD. Results Active smoking was the strongest risk factor after multiple adjustments (OR= 6.226, 95%CI = 1.561 ∼ 24.822), but passive smoking also was significantly associated with a risk of FSD (OR = 1.887, 95%CI = 1.092 ∼ 3.260) (p < .05). Other risk factors included age (OR = 1.040, 95%CI = 1.005 ∼ 1.076), medical comorbidities (OR= 1.688, 95%CI =1.044 ∼ 2.729), postmenopausal stage (OR= 2.021, 95%CI = 1.073 ∼ 5.717), and dissatisfied marital relations (OR= 3.771, 95%CI = 1.768 ∼ 8.045). The prevalence of FSD for smokers regarding disorders of sexual arousal, orgasm and sexual satisfaction increased in active smokers; sexual desire disorder, sexual arousal disorder and pain in secondhand smokers (p < .05). Conclusion The risk of FSD was closely related to depletion of ovarian function. Active smokers had the highest risk, but passive smoking also had a significant relationship to FSD. Although female smokers are rare in China, ‘husband smoking’ is frequent. Thus, our results should have significant healthcare consequences.