Abstract

Sleep apnoea is a common, yet underestimated, chronic disorder with a major impact on morbidity and mortality in the general population. It is quickly becoming recognized as an independent risk factor for cardiovascular impairment. Hypertension, coronary artery disease, diabetes, cardiovascular rhythm and conduction abnormalities, cerebrovascular disease, and heart failure have all been linked to this syndrome. This review will explore the critical connection between sleep apnoea and chronic cardiovascular diseases while highlighting established and emerging diagnostic and treatment strategies.

Highlights

  • Sleep apnoea is a common, yet underestimated, chronic disorder with a major impact on morbidity and mortality in the general population

  • Hypertension, coronary artery disease (CAD), diabetes, cardiovascular rhythm and conduction abnormalities, cerebrovascular disease, and heart failure (HF) have all been linked to this syndrome

  • The prevalence of sleep apnoea in the general population appears surprisingly high, even when bias is taken into account in both the selection of subjects referred for sleep studies and their willingness to participate

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Summary

Importance and management of chronic sleep apnoea in cardiology

Sleep apnoea is a common, yet underestimated, chronic disorder with a major impact on morbidity and mortality in the general population. It is quickly becoming recognized as an independent risk factor for cardiovascular impairment. Hypertension, coronary artery disease, diabetes, cardiovascular rhythm and conduction abnormalities, cerebrovascular disease, and heart failure have all been linked to this syndrome. This review will explore the critical connection between sleep apnoea and chronic cardiovascular diseases while highlighting established and emerging diagnostic and treatment strategies

Introduction
Pathophysiology of chronic sleep apnoea
Coronary artery disease and acute coronary syndrome
Heart failure
Pulmonary hypertension
Nocturnal oxygen supplementation
Phrenic nerve stimulation No proven or theoretical benefit
Findings
Conclusion

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