Abstract

In the wake of the rapid surge in the COVID-19-infected cases seen in Southern and West-Central USA in the period of June-July 2020, there is an urgent need to develop robust, data-driven models to quantify the effect which early reopening had on the infected case count increase. In particular, it is imperative to address the question: How many infected cases could have been prevented, had the worst affected states not reopened early? To address this question, we have developed a novel COVID-19 model by augmenting the classical SIR epidemiological model with a neural network module. The model decomposes the contribution of quarantine strength to the infection time series, allowing us to quantify the role of quarantine control and the associated reopening policies in the US states which showed a major surge in infections. We show that the upsurge in the infected cases seen in these states is strongly corelated with a drop in the quarantine/lockdown strength diagnosed by our model. Further, our results demonstrate that in the event of a stricter lockdown without early reopening, the number of active infected cases recorded on 14 July could have been reduced by more than 40% in all states considered, with the actual number of infections reduced being more than 100,000 for the states of Florida and Texas. As we continue our fight against COVID-19, our proposed model can be used as a valuable asset to simulate the effect of several reopening strategies on the infected count evolution, for any region under consideration.

Highlights

  • The Coronavirus respiratory disease 2019 originating from the virus “SARS-CoV-2” [1, 2] has led to a global pandemic, leading to more than 50 million confirmed global cases in more than 200 countries as of November 13, 2020 [3]

  • The QSIR model details are provided in Methods; Mean Absolute Percentage Error (MAPE) values for the model along with the epochs required for convergence for each state are provided in Supplementary Information

  • We have developed a novel methodology to quantify the effect of early reopening on the infected case count surge seen during the period of June-July 2020

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Summary

Introduction

The Coronavirus respiratory disease 2019 originating from the virus “SARS-CoV-2” [1, 2] has led to a global pandemic, leading to more than 50 million confirmed global cases in more than 200 countries as of November 13, 2020 [3]. Driven by disastrous situations in the states of Arizona, South Carolina, Texas, Florida, and Georgia [6], the surge in cases was later seen in several other Southern and West-Central states [9]. Early reopening seems to be corelated to the second surge of cases seen in the USA, there is a need

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