Abstract
to identify and synthesize studies on the effects of cannabis use and its relation with SARS-CoV-2, as well as the therapeutic possibilities of using cannabinoids in the prevention and treatment of COVID-19. scoping review, in the BVS, PubMed, SCIELO, CINAHL, SCOPUS, Web of Science, MedNar, CAPES and ProQuest databases, with no language restriction and year limitation. Narrative synthesis was performed. cannabis use causes changes in the respiratory and vascular system, it reduces the production of cytokines, which affects the users' immune system, increasing the susceptibility to infection and progression of COVID-19. However, studies have suggested the use of cannabinoids in the prophylaxis and treatment of COVID-19, due to their anti-inflammatory effect. the use of inhaled cannabis increases the progression and severity of the infection. On the other hand, the benefits of cannabinoids seem promising to modulate the immune system, but it needs further studies.
Highlights
In 2019, the world was surprised by the first contemporary pandemic, COVID-19 (Coronavirus Disease 2019), caused by Severe Acute Respiratory Syndromes (SARS)-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), which spread rapidly, causing death of more than 1900000 people[1]
A worrying factor is that about 25% of individuals present the infection asymptomatically[7], which further contributes to the rapid spread of the disease due to the lack of isolation necessary to contain the transmission[8], especially because these cases of asymptomatic infection are more common among young people, a population that least adheres to isolation measures[9]
And independently, the extracted data were verified and changes were made, if necessary. They carried out the quality assessment of the studies using the SUMARI software, through a critical evaluation checklist for experimental studies, expert opinion and review studies by the Joanna Briggs Institute (JBI)(22)
Summary
In 2019, the world was surprised by the first contemporary pandemic, COVID-19 (Coronavirus Disease 2019), caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), which spread rapidly, causing death of more than 1900000 people[1]. SARS-CoV-2 is part of the Coronaviridae family, which gets its name due to the appearance of a crown when viewed under electron microscopy[2] This coronavirus is responsible for causing respiratory syndrome and effects on other systems, such as the cardiac, renal[3] and central nervous system[4]. The disease caused by SARS-CoV-2 quickly reached pandemic status, reported by the World Health Organization (WHO) on March 11, 2020(6) In this context, a worrying factor is that about 25% of individuals present the infection asymptomatically[7], which further contributes to the rapid spread of the disease due to the lack of isolation necessary to contain the transmission[8], especially because these cases of asymptomatic infection are more common among young people, a population that least adheres to isolation measures[9]. The possibility of aggravation of the infection was verified in individuals considered more susceptible and prone to complications, including the older adults and people with clinical and chronic comorbidities (pulmonary, cardiovascular, cerebrovascular and diabetes)(10)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
