Abstract

Implications of 3-Year Follow-up Data From the Childhood and Adolescent Migraine Prevention Medication Trial

Highlights

  • The current study[1] presents interval follow-up data over a 3-year period for participants who were initially enrolled in the drug phase of Childhood and Adolescent Migraine Prevention Medication (CHAMP) and primarily interrogates whether participants maintained therapeutic gains after completion of the drug phase

  • The initial CHAMP trial[2] provided compelling evidence of what we already suspected— that is, treating pediatric migraine is not treating adult migraine with lower doses—it simultaneously incited serious debate among practitioners treating and researching pediatric headache

  • It seems that left without intervention, whether pharmacological or behavioral, a subset of pediatric patients will experience an increase in headache burden throughout childhood and into adulthood

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Summary

Introduction

The current study[1] presents interval follow-up data over a 3-year period for participants who were initially enrolled in the drug phase of CHAMP and primarily interrogates whether participants maintained therapeutic gains after completion of the drug phase. Migraine prevalence steadily increased throughout adolescence (15% in female and 7% in male individuals) and adulthood (22% in female and 8% in male individuals).[4] it seems that left without intervention, whether pharmacological or behavioral, a subset of pediatric patients will experience an increase in headache burden throughout childhood and into adulthood.

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