Abstract

Many medical disorders may contribute to adolescent psychoses. Although guidelines for thorough organicity investigations (OI) exist, their dissemination appears scarce in nonacademic healthcare facilities and some rare disorders remain undiagnosed, many of them presenting without easily recognized phenotypes. This study aims to understand the challenges underlying the implementation of OI in non-academic facilities by practitioners trained in expert centers. Sixteen psychiatrists working at French non-academic facilities were interviewed about their use of OI for adolescents suspected of early psychosis. Interviews were analyzed with Grounded Theory. Organicity investigations were found to be useful in rationalizing psychiatric care for the young patient all the while building trust between the doctor and the patient's parents. They also are reassuring for psychiatrists confronted with uncertainty about psychosis onset and the consequences of a psychiatric label. However, they commonly find themselves facing the challenges of implementation alone and thus enter a renunciation pathway: from idealistic missionaries, they become torn between their professional ethics and the non-academic work culture. Ultimately, they abandon the use of OI or delegate it to expert centers. Specific hindrances to OI implementation must be addressed.

Highlights

  • More than 60 diseases are known to increase the risk of psychotic disorders in childhood and adolescence; they include genetic syndromes, inborn errors of metabolism, and autoimmune, neurologic, endocrinological, and nutrition disorders [1,2,3]

  • Guidelines for thorough organicity investigations (OI) exist, their dissemination appears scarce in nonacademic healthcare facilities and some rare disorders remain undiagnosed, many of them presenting without recognized phenotypes

  • Sixteen psychiatrists working at French non-academic facilities were interviewed about their use of OI for adolescents suspected of early psychosis

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Summary

Introduction

More than 60 diseases are known to increase the risk of psychotic disorders in childhood and adolescence; they include genetic syndromes, inborn errors of metabolism, and autoimmune, neurologic, endocrinological, and nutrition disorders [1,2,3]. As many as 12.5% of cases of childhood psychosis may have a medical (somatic) disorder contributing to the clinical presentation (ex: homocystinuria or intermittent porphyria) but their frequency in non-academic settings may be inferior given their more generalist patient recruitment [3]. The involvement of such a disorder should be considered when the following signs are present: visual hallucinations, confusion, catatonia, fluctuating symptoms and intellectual deficiency, as well as when the course appears abnormal (early onset, sudden onset, progressive cognitive decline, or treatment resistance) [4]. Diagnosing medical and genetic causes and risk factors of early psychosis is a challenge [3] This challenge includes both training of psychiatrists and implementing organicity investigations throughout all psychiatric units. This study aims to understand the challenges underlying the implementation of OI in non-academic facilities by practitioners trained in expert centers

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