Abstract

Driven by recent innovations and technological progress, the increasing quality and amount of biomedical data coupled with the advances in computing power allowed for much progress in artificial intelligence (AI) approaches for health and biomedical research. In interventional cardiology, the hope is for AI to provide automated analysis and deeper interpretation of data from electrocardiography, computed tomography, magnetic resonance imaging, and electronic health records, among others. Furthermore, high-performance predictive models supporting decision-making hold the potential to improve safety, diagnostic and prognostic prediction in patients undergoing interventional cardiology procedures. These applications include robotic-assisted percutaneous coronary intervention procedures and automatic assessment of coronary stenosis during diagnostic coronary angiograms. Machine learning (ML) has been used in these innovations that have improved the field of interventional cardiology, and more recently, deep Learning (DL) has emerged as one of the most successful branches of ML in many applications. It remains to be seen if DL approaches will have a major impact on current and future practice. DL-based predictive systems also have several limitations, including lack of interpretability and lack of generalizability due to cohort heterogeneity and low sample sizes. There are also challenges for the clinical implementation of these systems, such as ethical limits and data privacy. This review is intended to bring the attention of health practitioners and interventional cardiologists to the broad and helpful applications of ML and DL algorithms to date in the field. Their implementation challenges in daily practice and future applications in the field of interventional cardiology are also discussed.

Highlights

  • In recent years, the field of interventional cardiology has been characterized by innovation and technological progress as clinicians, in partnership with specialists in molecular biology, biomedical engineering, biophysics and imaging technology, have raised interventional cardiology to a vibrant and dynamic subspecialty in mainstream medical practice

  • We first provide an overview of machine learning applications in interventional cardiology; subsequently, we discuss the demand for future improvements considering machine learning implementation challenges in daily practice and future applications in the field of interventional cardiology

  • Deep learning algorithms can currently perform all tasks required for automatic interpretation of coronary angiograms, such as identification of left/right coronary arteries, anatomy description, vessel segmentation, stenosis localization and stenosis severity prediction leading to reduced variability and higher standardization of diagnostic angiograms [46, 47]

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Summary

Frontiers in Cardiovascular Medicine

High-performance predictive models supporting decision-making hold the potential to improve safety, diagnostic and prognostic prediction in patients undergoing interventional cardiology procedures These applications include robotic-assisted percutaneous coronary intervention procedures and automatic assessment of coronary stenosis during diagnostic coronary angiograms. Machine learning (ML) has been used in these innovations that have improved the field of interventional cardiology, and more recently, deep Learning (DL) has emerged as one of the most successful branches of ML in many applications It remains to be seen if DL approaches will have a major impact on current and future practice. This review is intended to bring the attention of health practitioners and interventional cardiologists to the broad and helpful applications of ML and DL algorithms to date in the field Their implementation challenges in daily practice and future applications in the field of interventional cardiology are discussed

INTRODUCTION
MACHINE AND DEEP LEARNING OVERVIEW
MACHINE AND DEEP LEARNING FOR CARDIOVASCULAR APPLICATIONS
Type of algorithm
Support vector machine
Regularized regression
Principal component analysis
Shallow neural networks
Convolutional neural network Recurrent neural network
UNSUPERVISED DEEP LEARNING Autoencoder
REINFORCEMENT LEARNING Deep reinforcement learning
AI in the Real World
Domain Expertise
Overfitting and Interpretability
Missing Data
Final Comments
Findings
AUTHOR CONTRIBUTIONS
Full Text
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