Implementing a Multisite, Transdisciplinary Case-Control Study to Assess Effectiveness of Screening Colonoscopy for Preventing Death From Colorectal Cancer (SCOLAR)

Abstract

Background/Aims: Colorectal cancer (CRC) is the second leading cause of cancer death in the United States. There is a need for observational studies that assess effectiveness of “screening” colonoscopy by carefully defining indication for exam. “Screening for Colorectal Cancer in Average-Risk Adults (SCOLAR),” is a transdisciplinary study to determine if colonoscopy is as effective as believed, filling a critical void in the evidence on effectiveness of CRC screening interventions in reducing the risk of death in real-world practice.