Abstract
Active development of the pharmaceutical market shows a tendency to increase of pharmaceutical glass waste. The negative impact of waste on the environment shows itself in contamination of its elements by pharmaceutical substances contained in the waste, as well as the effects of medical glass and pathogens of infectious diseases. It was established that increasing of the ecologically safe handling of pharmaceutical glass waste and improvement of the disposal of glass can be provided by the method of electrochemical destruction of pharmaceutical substances. The optimal regimes and conditions to carry out the anodic oxidation process and the kinetic parameters of complete destruction of pharmaceutical substances (diclofenac, beta-estradiol, furosemide, atenolol, cefuroxime) were experimentally determined. The effectiveness of electrochemical destruction of five priority pharmaceutical substances, as well as their mixtures in a solution with sodium chloride using ORTA anode, was experimentally proved. It was established that complete destruction of pharmaceutical substances occurs during the process of electrochemical oxidation. It was noted that the introduction of this method makes it possible to destroy harmful pharmaceutical substances and to disinfect the solutions of pharmaceutical preparations infected with Escherichia coli bacteria in a single process. An additional positive effect of the introduction of the method is the improvement of the quality of pharmaceutical waste as a secondary material resource and promotion of the improvement in the technological processes of pharmaceutical waste disposal
Highlights
This occurs due to two factors: low concentrations of pharmaceutical substances in waste waters and the impossibility of adaptation of silt microbiota to new medicines that appear on the medicine market [8]
The aim of present study is to introduce a method of electrochemical destruction of pharmaceutical substances contained in pharmaceutical glass waste (PGW)
– to substantiate theoretically and to confirm experimentally the expediency of electrochemical destruction of pharmaceutical substances contained in PGW;
Summary
Formation and accumulation of pharmaceutical waste is becoming a global problem for society at present [1]. Pharmaceutical substances (PS) mainly contained in glass waste have the most harmful effect. Pharmaceutical pollutants get into surface waters mostly because of the lack of effective biological treatment at urban facilities This occurs due to two factors: low concentrations of pharmaceutical substances in waste waters and the impossibility of adaptation of silt microbiota to new medicines that appear on the medicine market [8]. Recycling and disinfecting methods of medical waste, which contain PGW in its composition, in most cases have disadvantages They relate to environmental factors (pollution of environmental elements, inefficient use of waste as a secondary material resource) [16,17,18,19]. First and foremost, it is necessary to include prevention of unacceptable environmental risk caused by PGW during waste collection and disposal to handling regulations
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