Abstract

The most common causes of blindness in adults worldwide, 2.6% of them are caused by diabetic retinopathy, which is a progressive disease caused by complications of diabetes mellitus. Early detection and prompt treatment help save eyesight. The artificial intelligence technology can provide objective and accurate screening results. Deep learning, especially the Convolutional Neural Network (CNN), which is part of artificial intelligence, has proven successful in solving image problems and is very well used in medical image analysis. CNN works well on large datasets, but it will affect network performance to overfitting in fewer datasets. So to solve the problem of small data, data augmentation techniques can be used. There are various kinds of data augmentation techniques. This study used the CNN method to classify diabetic retinopathy disease, compared several suitable data augmentation techniques for retinal fundus images, and used Contrast Limited Adaptive Histogram Equalization (CLAHE) for image enhancement. This study found that the augmented random zoom technique, together with CLAHE, provided the best accuracy of 98% with 96% sensitivity and 100% specificity.

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