Abstract
Extended-spectrum β-lactamase-producing Enterobacteriaceae (E-ESBLs) are an increasing problem all over the world due to their importance in nosocomial infections and these bacteria have been the cause of several important outbreaks. 1 Pena C. Pujol M. Ardanuy C. et al. Epidemiology and successful control of a large outbreak due to K. pneumoniae producing extended-spectrum β-lactamases. Antimicrob Agents Chemother. 1998; 42: 53-58 PubMed Google Scholar , 2 Moriguchi N. Itahashi Y. Tabata N. et al. Outbreak of CTX-M-3-type extended-spectrum beta-lactamase-producing Enterobacter cloacae in a pediatric ward. J Infect Chemother. 2007; 13: 263-266 Abstract Full Text PDF PubMed Scopus (14) Google Scholar , 3 Manzur A. Tubau F. Pujol M. et al. Nosocomial outbreak due to extended-spectrum-beta-lactamase-producing Enterobacter cloacae in a cardiothoracic intensive care unit. J Clin Microbiol. 2007; 45: 2365-2369 Crossref PubMed Scopus (47) Google Scholar In Belgium, nosocomial infections with E-ESBLs have gradually increased over the last 15 years. 4 De Gheldre Y. Glupczynski Y. Struelens M. De Mol P. Emergence of E.aerogenes as a major antibiotic resistant nosocomial pathogen in Belgian hospitals. Clin Microbiol Infect. 1999; 5: 622-627 Crossref PubMed Scopus (25) Google Scholar
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