Implementation of a family history questionnaire to identify patients appropriate for hereditary cancer testing.

Abstract

e12504 Background: The NCCN has developed guidelines for identifying and testing patients for Hereditary Breast and Ovarian Cancer (HBOC) syndrome, due to mutations in BRCA1 or BRCA2, and Lynch syndrome (LS), due to mutations in MLH1, MSH2, MSH6, PMS2 or EPCAM. In order to follow these guidelines, standard methods for collecting patient and family cancer history and acting on this information should be established. In response to ASCO’s QOPI family history initiative, we examined hereditary cancer testing at a 5-physician oncology practice that was already testing for hereditary cancer to determine what percentage of patients were missed based on family history. Methods: Historically, family histories were taken orally by the treating physician without a specific or consistent set of questions. Patients who met NCCN criteria were then referred to a practice physician (S.D.) for counseling and testing. For the week of November 18th 2013, a cancer family history questionnaire (FHQ) was given to every patien...