Abstract
to evaluate the refractive and visual results of a new treatment for keratoconus using the corneal intrastromal implantation system (CISIS). six eyes of four patients with keratoconus were treated with CISIS. Follow-up was 1, 3, and 6 months. After creating an intracorneal pocket of 9-mm diameter and 300-microm depth, a flexible full-ring implant was inserted via a 4-mm-wide corneal tunnel. no eyes showed loss of lines in uncorrected distance visual acuity (UDVA) or spectacle corrected distance visual acuity (CDVA) at any follow-up examination. Uncorrected and distance corrected visual acuity, keratometry, spherical and cylindrical refractive error as well as spherical equivalent refraction improved significantly (P<.05). Mean UDVA improved from 20/260 to 20/48 and mean CDVA improved from 20/41 to 20/27. A significant centralization and decrease of the corneal apex was found. No intra- or postoperative complications were observed. the corneal intrastromal implantation system using a complete ring implanted in a stromal pocket can achieve significant improvements in the visual function of patients with keratoconus. Uncorrected distance visual acuity improved by more than seven lines on average and CDVA improved by two lines.
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