Abstract
Interest in implantable microchips for medical sensors is increasing. To reduce the invasiveness of implantation, wireless data transmission in a living body is an important issue shared by all such sensors. Here, the authors report on a light-based wireless data transmission method for implantable biomedical sensor chips. An implantable micro-sized image sensor (400 × 1200 μm2) that was designed to modulate a small light-emitting diode (λ = 855 nm) with pulse-width modulation for intra-vital optical communication (IOC) was developed. Both a transmitter device and a receiver device for IOC were prepared, and optical image data transmission through biological tissue (a mouse skull bone) was successfully demonstrated.
Highlights
Recent advances in implantable microchips based on semiconductor technology for physiological monitoring from inside the body are becoming an increasing interest in both fundamental research [1] and medical applications [2]
The Complementary–metal–oxide semiconductor (CMOS)-based implantable microchip technology is attractive for physiological monitoring inside the body for medical use [3, 4]
We proposed the application of intra-body communication (IBC) to implantable medical sensors as a wireless data transmission method [6, 7]
Summary
Recent advances in implantable microchips based on semiconductor technology for physiological monitoring from inside the body are becoming an increasing interest in both fundamental research [1] and medical applications [2]. We proposed the application of intra-body communication (IBC) to implantable medical sensors as a wireless data transmission method [6, 7]. Such a data transmission approach using electric current can only be applied in a conductive medium. We describe the implantable image sensor, which was designed to modulate the micro-LED to optically transmit image data Both a transmitter device and a receiver device were prepared and image data transmission with IOC via the skull bone as a non-conductive medium was demonstrated
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